Metafolin is a trademarked name for the active form of folate, known as methylfolate. While Optimized Folate doesn't utilize this specific brand, it does include L-Methylfolate.

Life ExtensionOptimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets

Life ExtensionOptimized Folate (L-Methylfolate) – Supports Heart & Brain Health – Non-GMO, Gluten-Free, Vegetarian –1700 mcg DFE — 100 Vegetarian Tablets

Q: It says 1700 mcf DFE of folate, but how of that is actual folic acid equivalent?

Hello, We apologize for any confusion. At the end of August of 2020, we updated our Optimized Folate supplement facts section. The amount of folate was updated from 1,000 mcg to 1,700 mcg based on updated FDA labeling guidelines. This change is a result of what the FDA has defined as dietary folate equivalents (DFE). They determined that 0.6 mcg of (6S)-5-methyltetrahydrofolate, calcium salt is equal to 1 mcg DFE. They have also determined that one mcg of naturally occurring folate is equal to one mcg DFE. Their rationale is that this accounts for the greater bioavailability (6S)-5-methyltetrahydrofolate, calcium salt compared to naturally occurring folate. The change to 1,700 mcg in this product allows us to deliver the desired potency in terms of DFE.

Q: What is the expiration date?

The expiration date on mine is 7/20/2023, but I bought it over 3 months ago. I have no idea what the expiration date will be on the bottle you’re buying.

Q: Is any component of your usa manufactured product sourced from china or india?

It's been a very long time since I purchased this product. I no longer have the container and have consumed all of the product. That said, I have since switched to Folic Acid 800 mcg made in Austin Texas and available on Amazon.

Product ID: 258199059

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Details

Brand
Life Extension
Item form
Tablet
Primary supplement type
Folate as salt
Diet type
Gluten Free
Flavour
Unflavored

💊1700 mcg bioactive L-Methylfolate

🧠Boosts cognitive function & brain health

❤️Supports heart health via homocysteine balance

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Description

💡 Elevate your heart and mind with every tablet — don’t miss out on optimized wellness!

PURE CLEAN FORMULA - Non-GMO, gluten-free, vegetarian tablets crafted in the USA
HEART BRAIN SYNERGY - Clinically linked to maintaining healthy homocysteine levels
DAILY WELLNESS MADE SIMPLE - One tablet a day supports your long-term cardiovascular and cognitive vitality
BIOACTIVE FOLATE POWERHOUSE - 1700 mcg of 5-MTHF for instant metabolic absorption
SCIENTIFICALLY BACKED DOSAGE - Formulated with research-driven ingredient potency for maximum efficacy

Life Extension Optimized Folate delivers 1700 mcg of metabolically active L-Methylfolate per vegetarian tablet, supporting cardiovascular and cognitive health by maintaining healthy homocysteine levels. This non-GMO, gluten-free supplement is crafted in the USA with premium ingredients, designed for adults seeking scientifically validated daily support for heart and brain vitality.

Specifications

Product Name	L-Methylfolate Supplement
Additives	microcrystalline cellulose, dicalcium phosphate, croscarmellose sodium, silica, vegetable stearate, stearic acid.
Allergen Information	Gluten Free, Non-GMO
Weight	0.2 Kilograms
Units	100 Count
Serving Recommendation	Take one (1) tablet daily
Brand	Life Extension
Format	Tablet
Age Range Description	Adult

Have a Question? See What Others Asked

It says 1700 mcf DFE of folate, but how of that is actual folic acid equivalent?

What is the expiration date?

Is this Metafolin?

Is any component of your usa manufactured product sourced from china or india?

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